We are focusing on the following settings, that bring the highest compatibility and accuracy when playing the game:
-Merged ISO for PSP with CFW PRO @ 30fps.
Why PSP @ 30fps? Because the game is meant to be played on a PSP at that frame rate.
Why the Merged ISO? Because translating one ISO is way, but WAAAYYYY simpler than translating 2, in terms of romhacking.
Why PRO CFW? Because it's the only one that can play ISO's bigger than 2 GB with absolutely no problem.
There are many other possible settings, involving:
-Platform: it can be either PSP, PsVita, PS3, PC, or Android (guess IOS should work alright too, basically every platform where PPSSPP can be present).
-ISO Mode: Merged or separated.
-Native Frame rate: 60, 30 or 15 (7.5 fps is also possible but come on lol xD).